Detalhe da pesquisa
1.
Discovery and functional interrogation of SARS-CoV-2 RNA-host protein interactions.
Cell
; 184(9): 2394-2411.e16, 2021 04 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-33743211
2.
Genome-wide CRISPR Screens Reveal Host Factors Critical for SARS-CoV-2 Infection.
Cell
; 184(1): 76-91.e13, 2021 01 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33147444
3.
Live imaging of SARS-CoV-2 infection in mice reveals that neutralizing antibodies require Fc function for optimal efficacy.
Immunity
; 54(9): 2143-2158.e15, 2021 09 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-34453881
4.
PLSCR1 is a cell-autonomous defence factor against SARS-CoV-2 infection.
Nature
; 619(7971): 819-827, 2023 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-37438530
5.
Comprehensive in vivo secondary structure of the SARS-CoV-2 genome reveals novel regulatory motifs and mechanisms.
Mol Cell
; 81(3): 584-598.e5, 2021 02 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33444546
6.
Inflammasome activation in infected macrophages drives COVID-19 pathology.
Nature
; 606(7914): 585-593, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35483404
7.
Intranasal neomycin evokes broad-spectrum antiviral immunity in the upper respiratory tract.
Proc Natl Acad Sci U S A
; 121(18): e2319566121, 2024 Apr 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-38648490
8.
DYRK1A promotes viral entry of highly pathogenic human coronaviruses in a kinase-independent manner.
PLoS Biol
; 21(6): e3002097, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37310920
9.
Genome-wide CRISPR activation screen identifies JADE3 as an antiviral activator of NF-kB-dependent IFITM3 expression.
J Biol Chem
; 300(4): 107153, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38462163
10.
The KDM6A-KMT2D-p300 axis regulates susceptibility to diverse coronaviruses by mediating viral receptor expression.
PLoS Pathog
; 19(7): e1011351, 2023 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-37410700
11.
Human iPSC-Based Model of COPD to Investigate Disease Mechanisms, Predict SARS-COV-2 Outcome, and Test Preventive Immunotherapy.
Stem Cells
; 42(3): 230-250, 2024 Mar 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-38183264
12.
LRRC15 inhibits SARS-CoV-2 cellular entry in trans.
PLoS Biol
; 20(10): e3001805, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36228039
13.
Tuft cells are key mediators of interkingdom interactions at mucosal barrier surfaces.
PLoS Pathog
; 18(3): e1010318, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35271673
14.
Reovirus infection is regulated by NPC1 and endosomal cholesterol homeostasis.
PLoS Pathog
; 18(3): e1010322, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35263388
15.
Single-cell longitudinal analysis of SARS-CoV-2 infection in human airway epithelium identifies target cells, alterations in gene expression, and cell state changes.
PLoS Biol
; 19(3): e3001143, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33730024
16.
Coronavirus Lung Infection Impairs Host Immunity against Secondary Bacterial Infection by Promoting Lysosomal Dysfunction.
J Immunol
; 209(7): 1314-1322, 2022 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36165196
17.
Translational shutdown and evasion of the innate immune response by SARS-CoV-2 NSP14 protein.
Proc Natl Acad Sci U S A
; 118(24)2021 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34045361
18.
Restriction of SARS-CoV-2 replication by targeting programmed -1 ribosomal frameshifting.
Proc Natl Acad Sci U S A
; 118(26)2021 06 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-34185680
19.
UFMylation inhibits the proinflammatory capacity of interferon-γ-activated macrophages.
Proc Natl Acad Sci U S A
; 118(1)2021 01 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33372156
20.
Restriction of Viral Replication, Rather than T Cell Immunopathology, Drives Lethality in Murine Norovirus CR6-Infected STAT1-Deficient Mice.
J Virol
; 96(6): e0206521, 2022 03 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-35107369